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Thread · #bloodwork · 2025-01-30

apoB versus LDL-C, the short version of a long argument

Spun off from a message in #bloodwork on 2025-01-30. 5 messages, 3 participants.

The message this came from
  • peak_split — pulling it out so nobody has to scroll for it again 22:58
PS

LDL-C: cholesterol mass carried in LDL. cheap, everywhere, in every guideline

apoB: one apoB per atherogenic particle, so it is a count. more informative when triglycerides are high

SN

practical version: get both if you can. if you can only get one and your trigs are over about 2 mmol/L, apoB tells you more

PS

non-HDL-C is the free compromise. it is already on every lipid panel and nobody looks at it

BV

and the counterpoint stands. the outcome trials and the guidelines are built on LDL-C, so that is what your doctor will treat