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#cagrilintide 2024-11-28

Thursday9 messages4 participantstimes are UTC
Highlights from this day
  • maintenance_mo — amylin is about slowed gastric emptying and satiety signalling, thats the short version and im no pharmacologist 18:52
  • deamidation — the nausea felt different rather than less, more fullness and less of the queasy wave, ymmv 18:58
  • deamidation — dropped the GLP-1 and stayed on this alone for 22 months, appetite held but weight barely moved 19:14
MM
maintenance_mo18:52

amylin is about slowed gastric emptying and satiety signalling, thats the short version and im no pharmacologist

DE
deamidationlab18:54

CagriSema is cagrilintide with semaglutide and REDEFINE is the trial programme around it

stopped for 18 months and the fullness went within a fortnight of the last dose

the nausea felt different rather than less, more fullness and less of the queasy wave, ymmv

KF
karl_fischer19:02

monotherapy question, did appetite move for you without a GLP-1 alongside

DE
deamidationlab19:14

dropped the GLP-1 and stayed on this alone for 22 months, appetite held but weight barely moved

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