you cannot tell which of the two is doing what in a combination and i stopped pretending i could, ill dig out the number
#cagrilintide 2025-03-22
- reta_resting_hr — you cannot tell which of the two is doing what in a combination and i stopped pretending i could, ill dig out the number 12:37
- reta_resting_hr — dosing them on different days made no difference i could detect, we shall see 12:43
- evidence_or_not — added it to an existing retatrutide dose rather than starting both, which made attribution possible i was sceptical about monotherapy and after 6 months im still… 13:00
dosing them on different days made no difference i could detect, we shall see
CagriSema is cagrilintide with semaglutide and REDEFINE is the trial programme around it
monotherapy was underwhelming for me and i say that as someone who wanted it to work
anyone stopped the GLP-1 and kept only this
monotherapy here
2 in 0.5ml gives 4mg/ml which is what i use, purely because the units come out round
i keep the two on separate days so if something goes wrong i have a chance of knowing which
REDEFINE is the phase 3 programme, most of what gets quoted casually in here is earlier work
added it to an existing retatrutide dose rather than starting both, which made attribution possible
i was sceptical about monotherapy and after 6 months im still sceptical, just less so