back after 20 months, is monotherapy still a minority thing here
#cagrilintide 2025-07-19
Saturday11 messages3 participantstimes are UTC
Highlights from this day
- HPLC_Hank — amylin is about slowed gastric emptying and satiety signalling, thats the short version and im no pharmacologist 15:49
- HPLC_Hank — the nausea felt different rather than less, more fullness and less of the queasy wave its an amylin analogue, different receptor family, so treating it as another… 15:52
- melb_meniscus — slightly off topic but the fullness thing is the part people describe differently, food stops being interesting rather than repellent 15:56
- melb_meniscus — weekly for me, same day every week, no reason beyond habit monotherapy was underwhelming for me and i say that as someone who wanted it to work 16:13
- HPLC_Hank — did the nausea feel different to you or just less 18:23
amylin is about slowed gastric emptying and satiety signalling, thats the short version and im no pharmacologist
the nausea felt different rather than less, more fullness and less of the queasy wave
its an amylin analogue, different receptor family, so treating it as another GLP-1 is the first mistake
slightly off topic but the fullness thing is the part people describe differently, food stops being interesting rather than repellent
👀3📈16✅17
weekly for me, same day every week, no reason beyond habit
monotherapy was underwhelming for me and i say that as someone who wanted it to work
its an amylin analogue, different receptor family, so treating it as another GLP-1 is the first mistake
*VendorInvestigate not the other one
i said earlier this year that monotherapy did nothing for me, and at a higher dose it did something
did the nausea feel different to you or just less
👀7
titrating dead slow
quick one £120 for a 30 vial and it lasts me longer than the GLP-1 does at my doses