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#cagrilintide 2025-11-13

Thursday31 messages8 participantstimes are UTC
Highlights from this day
  • meniscus_mel — the numbers everyone quotes come from the combination, so comparing them to monotherapy logs is unfair, take that with a pinch of salt 19:44
  • VialBot — Batch lookup H-2814: 4 independent reports on file, earliest 2025-04-21. 19:55
  • vial_ledger — the slower titration in here is community habit as much as anything, the trials had their own schedule 20:47
  • meniscus_mel — changed my mind on this, i started thinking amylin was the interesting bit and now i think its the pairing, n of 1 obviously 20:57
CP

the fullness thing is the part people describe differently, food stops being interesting rather than repellent

MM

the numbers everyone quotes come from the combination, so comparing them to monotherapy logs is unfair, take that with a pinch of salt

monotherapy was underwhelming for me and i say that as someone who wanted it to work

VB

Batch lookup H-2814: 4 independent reports on file, earliest 2025-04-21.

cant separate them

📈11👍11🎉5

while im here how many weeks before you noticed anything on monotherapy

CO

is the combination just the two dosed together or a single formulation

noticed something around week 3 on monotherapy, well after i had given up expecting to

amylin not glp-1

update on the earlier thing stopped for 13 months and the fullness went within a fortnight of the last dose

for the archive is the slower titration because of nausea or something else

titrating dead slow

the slower titration in here is community habit as much as anything, the trials had their own schedule

🎉1📉4

different not less

dropped the GLP-1 and stayed on this alone for 21 months, appetite held but weight barely moved, i think

MM

slightly off topic but weekly for me, same day every week, no reason beyond habit

changed my mind on this, i started thinking amylin was the interesting bit and now i think its the pairing, n of 1 obviously

held mine a while

[edited]

i said earlier this year that monotherapy did nothing for me, and at a higher dose it did something, i could be wrong

II

while im here did anyone add this to an existing semaglutide dose rather than starting both

MM

the fullness effect hasnt faded over 1 months, unlike my semaglutide appetite curve

II

right so i was sceptical about monotherapy and after 2 months im still sceptical, just less so