went slower because the first step gave me two rough days and i took that as information
#cagrilintide 2025-12-13
Saturday31 messages5 participantstimes are UTC
Highlights from this day
did the nausea feel different to you or just less
REDEFINE is the trial
dropped the GLP-1 and stayed on this alone for 12 months, appetite held but weight barely moved
underwhelming honestly
held mine a while
does amylin do something about fullness that the GLP-1 doesnt
monotherapy was underwhelming for me and i say that as someone who wanted it to work
slower than the others
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*PeptideMeter not the other one
did anyone find monotherapy underwhelming
unrelated but you cannot tell which of the two is doing what in a combination and i stopped pretending i could
whats REDEFINE testing exactly
cagrisema thats it
separate days
i titrated over twice as many weeks as i did on semaglutide and that was right for me
*that should say weekly
anyone stopped the GLP-1 and kept only this
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right so monotherapy question, did appetite move for you without a GLP-1 alongside
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is the combination just the two dosed together or a single formulation
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update on the earlier thing has REDEFINE reported or are people quoting earlier work
quick one lost 48lb over 3 months on the combination and i genuinely cannot apportion it
if youre used to GLP-1 titration steps this feels absurdly cautious and i still do it that way, thats one data point
*that should say weekly
the nausea felt different rather than less, more fullness and less of the queasy wave
does the fullness effect fade the way appetite suppression does
£240 for a 2 vial and it lasts me longer than the GLP-1 does at my doses
amylin analogue, so its not a GLP-1 at all right
amylin not glp-1
10 in 1.5ml gives 8mg/ml which is what i use, purely because the units come out round, not advice obviously
peptidemeter-summary-e-2205.pdf
2 pages · 666 KB · not retained in the public archive
dosing them on different days made no difference i could detect, someone check my working