does the fullness effect fade the way appetite suppression does
[edited]#cagrilintide 2026-05-12
Tuesday14 messages5 participantstimes are UTC
Highlights from this day
- blind_submit — how do people separate which of the two is doing what in a combination 20:49
- blind_submit — sorry to jump in amylin is about slowed gastric emptying and satiety signalling, thats the short version and im no pharmacologist 20:54
- peak_split — two Janoshik results on the same WXT lot came back 99.4 and 99.2, closer than i expected 21:16
- clove_charts — is the combination just the two dosed together or a single formulation 21:20
how do people separate which of the two is doing what in a combination
medutest-report-h-2814.pdf
3 pages · 555 KB · not retained in the public archive
REDEFINE is the phase 3 programme, most of what gets quoted casually in here is earlier work
sorry to jump in amylin is about slowed gastric emptying and satiety signalling, thats the short version and im no pharmacologist
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follow up the fullness thing is the part people describe differently, food stops being interesting rather than repellent
two Janoshik results on the same WXT lot came back 99.4 and 99.2, closer than i expected
dosing them on different days made no difference i could detect
is the combination just the two dosed together or a single formulation
site-rotation-map.png
1000 × 700 · 763 KB · not retained in the public archive
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is the slower titration because of nausea or something else
separate days
did the nausea feel different to you or just less
held at 2 for 5 months on monotherapy before i touched it again
sorry to jump in is there a reason people titrate this over more weeks than the others
REDEFINE is the trial