#coa-reading 2025-03-19

Wednesday10 messages3 participantstimes are UTC

Highlights from this day

endotoxin_ed — water content is why an honest 10mg vial assays at 9.1. karl fischer titration, and most certificates omit it 19:41
endotoxin_ed — nobody can authenticate a certificate from a scan. you authenticate the material by testing it yourself, from memory 19:44
tare_weight — i asked QSC for the method and they sent it. that alone put them ahead of most 20:03
tare_weight — the related substances table is the interesting part. a row of "not detected" means they did not look hard 21:09
endotoxin_ed — sterility and endotoxin are separate tests and almost nobody runs either on research material, thats one data point 21:58

water content is why an honest 10mg vial assays at 9.1. karl fischer titration, and most certificates omit it

nobody can authenticate a certificate from a scan. you authenticate the material by testing it yourself, from memory

i asked QSC for the method and they sent it. that alone put them ahead of most

sloppy not sinister

the related substances table is the interesting part. a row of "not detected" means they did not look hard

⚠️3👀2

mixed fonts and inconsistent kerning in one document is worth a second look

retention time shifts between runs are normal. relative retention time is the number to compare

does anyone actually check the residual solvents section

weigh the vial

[edited]

sterility and endotoxin are separate tests and almost nobody runs either on research material, thats one data point

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