same chromatogram
#coa-reading 2025-04-15
Tuesday13 messages5 participantstimes are UTC
Highlights from this day
- abdo_two_inch — water content is why an honest 10mg vial assays at 9.1. karl fischer titration, and most certificates omit it 19:04
- deamidation — sterility and endotoxin are separate tests and almost nobody runs either on research material 19:36
- salt_bridge — net peptide is gross mass minus water minus counterion. that is why 11.4mg of powder can be a correct 10mg vial 20:13
unrelated but is a supplier certificate worth anything on its own
water content is why an honest 10mg vial assays at 9.1. karl fischer titration, and most certificates omit it
what does net peptide content mean next to gross mass
is endotoxin ever tested on research material
sterility and endotoxin are separate tests and almost nobody runs either on research material
✅16
not evidence on its own
net peptide is gross mass minus water minus counterion. that is why 11.4mg of powder can be a correct 10mg vial
if the certificate date precedes the lot date, ask. sometimes it is sloppiness and sometimes it is not
[edited]no lot no certificate
an identical chromatogram on two different lots is the single biggest tell there is
is there a standard layout or does every lab do their own
how do you verify a certificate is actually from the lab it says