is endotoxin ever tested on research material
#coa-reading 2025-07-10
Thursday26 messages7 participantstimes are UTC
Highlights from this day
- split_dose_sam — a lab that reports "greater than 98%" rather than a number is telling you they did not integrate carefully 23:06
- split_dose_sam — retention time shifts between runs are normal. relative retention time is the number to compare 23:14
- night_pin — purity is what fraction of the contents is the target. assay is how many mg are actually there. different questions 23:28
- dark_for_ten_days — nobody can authenticate a certificate from a scan. you authenticate the material by testing it yourself, your mileage will differ 23:42
- swab_dry_first — what does net peptide content mean next to gross mass 23:58
is water content normally on a certificate or do you have to ask
no lot no certificate
check the lot
a lab that reports "greater than 98%" rather than a number is telling you they did not integrate carefully
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the honest summary is that a certificate tells you what the supplier says about a lot they chose to test
[edited]purity is not assay
my 40mg vial weighed more than 2mg of powder, is the certificate lying
thats a real table
retention time shifts between runs are normal. relative retention time is the number to compare
👀3
i have never seen a research certificate with an endotoxin result on it. not once
whats the related substances table actually telling me
does anyone keep a folder of certificates to compare over time
does anyone actually check the residual solvents section
thats the counterion
purity is what fraction of the contents is the target. assay is how many mg are actually there. different questions
is area percent the same thing as how many mg are in the vial
mixed fonts and inconsistent kerning in one document is worth a second look, i think
net not gross
thats a tell
sloppy not sinister
nobody can authenticate a certificate from a scan. you authenticate the material by testing it yourself, your mileage will differ
update from 19 months ago: started asking every supplier for water content and about half now include it
looks re-dated
whats the minimum a certificate has to have before you take it seriously
what does net peptide content mean next to gross mass
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