vialroom

#coa-reading 2026-03-10

Tuesday12 messages3 participantstimes are UTC
Highlights from this day
  • area_percent — retention time shifts between runs are normal. relative retention time is the number to compare, i could be wrong 22:10
  • area_percent — purity is what fraction of the contents is the target. assay is how many mg are actually there. different questions 22:29
  • area_percent — residual solvents matter more than people think for anything that went through a lot of purification steps 22:54
  • area_percent — water content is why an honest 10mg vial assays at 9.1. karl fischer titration, and most certificates omit it 22:56
BB

sterility and endotoxin are separate tests and almost nobody runs either on research material

BB

thats a real table

janoshik-a-2601.pdf
2 pages · 174 KB · not retained in the public archive

my 5mg vial weighed more than 5mg of powder, is the certificate lying

AP

retention time shifts between runs are normal. relative retention time is the number to compare, i could be wrong

AP

is area percent the same thing as how many mg are in the vial

🤝1

purity is what fraction of the contents is the target. assay is how many mg are actually there. different questions

🙏141😂7
AP

certificate is dated before the lot date, is that just sloppiness

residual solvents matter more than people think for anything that went through a lot of purification steps

water content is why an honest 10mg vial assays at 9.1. karl fischer titration, and most certificates omit it

right so how do you verify a certificate is actually from the lab it says