retention time shifts between runs are normal. relative retention time is the number to compare
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#coa-reading 2026-05-10
Sunday14 messages3 participantstimes are UTC
Highlights from this day
- quiet_head_qi — retention time shifts between runs are normal. relative retention time is the number to compare 16:55
- quiet_head_qi — a supplier certificate on its own is a starting point, not evidence. that is the whole reason the verification channel exists, thats one data point 17:57
- quiet_head_qi — a vial can be 99.4% pure and hold 8.1mg of a 10mg label. both numbers are true and only one of them is the one you care about, not advice obviously 18:24
- dublin_dose — i was wrong about this for a year: area percent under-reports nothing, it just answers a different question than assay does, i think 18:29
the retention time on this one is different from the last lot, problem
no lot no certificate
a supplier certificate on its own is a starting point, not evidence. that is the whole reason the verification channel exists, thats one data point
quick one net peptide is gross mass minus water minus counterion. that is why 11.4mg of powder can be a correct 10mg vial
what does net peptide content mean next to gross mass
no lot number, no certificate. a document you cannot tie to the vial in your hand is decoration, still working it out
net not gross
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a vial can be 99.4% pure and hold 8.1mg of a 10mg label. both numbers are true and only one of them is the one you care about, not advice obviously
coa-d-0718.pdf
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not detected means nothing
purity is not assay
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i was wrong about this for a year: area percent under-reports nothing, it just answers a different question than assay does, i think
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good certificate actually
test it yourself