hold
#dosing-titration 2024-03-27
Wednesday26 messages8 participantstimes are UTC
Highlights from this day
- ferrous_ash — dose day drift is mostly harmless with a weekly compound, but pick a day and defend it 04:06
- HPLC_Hank — if you are going up because the scale stalled for two weeks, wait. two weeks is noise 04:18
- HPLC_Hank — after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice 04:20
- slow.taper — holding is not failing. most people here who lasted two years held at least one dose for months 04:25
- VialBot — Reminder set. I will post here in 9 days. 05:12
is week 23 too early to be thinking about the next step
i would hold
dose day drift is mostly harmless with a weekly compound, but pick a day and defend it
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with a roughly seven day half-life you are near steady state after about five weeks at a dose
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if you are going up because the scale stalled for two weeks, wait. two weeks is noise
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coming back to this nobody here can tell you what dose to be on and the ones who try get corrected, your mileage will differ
after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice
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is it normal for appetite to come back at the end of the week
the ladder in the trials is a starting point, not a schedule you owe anyone
holding is not failing. most people here who lasted two years held at least one dose for months
coming back to this the trials escalated on a fixed schedule because a trial has to. you are not a trial
do you count from injection day or from when you actually felt it
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i log dose, day, weight and one line about how the week felt. thats enough to make decisions on
i escalate on symptoms. if the current dose is still doing something i stay on it
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follow up i have been at 0.5 for 24 months and honestly i have stopped wanting to move
stepping back down on purpose is a completely reasonable move and this channel should say so more often
my rule: if a side effect is still there at day five, i hold. if it clears by day three, i step, thats one data point
go slower
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how do you tell a plateau from just being at your set point
the honest answer is that most of us are running protocols nobody has ever studied
if it "stopped working after four days" that is almost never pharmacokinetics
Reminder set. I will post here in 9 days.
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thats anecdote
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if it "stopped working after four days" that is almost never pharmacokinetics
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