whats the longest anyone has stayed on one dose
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#dosing-titration 2024-08-08
Thursday18 messages5 participantstimes are UTC
Highlights from this day
- low_and_slow — whats the longest anyone has stayed on one dose 10:43
- food_noise_off — the ladder in the trials is a starting point, not a schedule you owe anyone 13:54
- plateau_pen — if i hold at 12 indefinitely am i losing anything 15:05
- food_noise_off — my dose day has drifted 4 days later over 9 months, does it matter 15:37
slightly off topic but came down from a treatment dose to maintenance over about three months and it was uneventful
dose day drift is mostly harmless with a weekly compound, but pick a day and defend it
follow up coming down from 1 to 0.25, how bad is the appetite rebound
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hold
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holding is not failing. most people here who lasted two years held at least one dose for months
how do you decide between holding and stepping when both feel wrong
if the current dose is still working, going up is spending headroom you might want later
the ladder in the trials is a starting point, not a schedule you owe anyone
coa-a-2418.pdf
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update question: did anyone who held for 10 months regret it
the argument for splitting is a flatter curve. the argument against is you have doubled your injections for a guess
if i hold at 12 indefinitely am i losing anything
[edited]pick a day and stick to it
thats anecdote
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my dose day has drifted 4 days later over 9 months, does it matter
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slightly off topic but the trials escalated on a fixed schedule because a trial has to. you are not a trial
plateau versus set point is not answerable in under six months of data
the honest answer is that most of us are running protocols nobody has ever studied