steady state is 5 weeks
#dosing-titration 2024-08-26
Monday32 messages8 participantstimes are UTC
Highlights from this day
split dosing has no trial behind it. people here do it and report on it, thats all
plateau versus set point is not answerable in under six months of data
half life is a week
*week 20 not week 4
right so nobody here can tell you what dose to be on and the ones who try get corrected
no trial for that
i have been at 2.4 for 2 months and honestly i have stopped wanting to move
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i went from 1.7 to 0.25 and honestly could not tell the difference in appetite
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how do you tell a plateau from just being at your set point
Inter-lab diff for lot D-0718: 98.1% vs 97.4%. Within expected range.
a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored
holding is not failing. most people here who lasted two years held at least one dose for months
if i hold at 2.5 indefinitely am i losing anything
i would hold
whats the longest anyone has stayed on one dose
end of week thing
my titration ladder took 12 months to climb and i would do it slower again
appetite returning at the end of the week is extremely common and is not the dose failing
whats a sensible maintenance dose after a year at treatment dose
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is there a point where going up stops buying you anything
[edited]i escalate on symptoms. if the current dose is still doing something i stay on it, ymmv
if you are going up because the scale stalled for two weeks, wait. two weeks is noise
thats normal
lean_mass_lexi escalate on symptoms. if the current dose is still doing something i stay on it, ymmv
update on the earlier thing dose day drift is mostly harmless with a weekly compound, but pick a day and defend it
does a missed week reset anything or do you just carry on
appetite returning at the end of the week is extremely common and is not the dose failing
i hold for two months minimum before i decide a dose has stopped doing anything
small steps are better than big ones and the only reason people take big ones is impatience
if the current dose is still working, going up is spending headroom you might want later
sorry to jump in you do not have to escalate at all. that is a real option that gets forgotten
split_dose_sama missed week does not reset you, but going straight back to the top dose after a gap…
i went up too fast and im paying for it, do i drop back or ride it out
coming back to this whats the smallest step anyone has managed between doses