vialroom

#dosing-titration 2025-04-11

Friday17 messages3 participantstimes are UTC
Highlights from this day
  • tenpence — dose day drift is mostly harmless with a weekly compound, but pick a day and defend it 19:16
  • tenpence — what does the room think about jumping a rung to catch up 19:52
  • point_two_five — whats a sensible maintenance dose after a year at treatment dose 20:23
  • tenpence — stepping back down on purpose is a completely reasonable move and this channel should say so more often 20:24
TE

dose day drift is mostly harmless with a weekly compound, but pick a day and defend it

medutest-report-a-2418.pdf
3 pages · 560 KB · not retained in the public archive
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held for months

MC

appetite returning at the end of the week is extremely common and is not the dose failing

MC

sorry to jump in is there any actual reason to escalate every 4 weeks other than the trial did it

PT

i jumped a rung once to catch up after a supply gap and it was a bad week. would not repeat

PT

is there a trial anywhere that studied twice weekly, or is it all anecdote

TE

what does the room think about jumping a rung to catch up

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TE

stepping back down on purpose is a completely reasonable move and this channel should say so more often

[edited]
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sorry to jump in is there a point where going up stops buying you anything

*Medutest not the other one

the honest answer is that most of us are running protocols nobody has ever studied, ymmv