vialroom

#dosing-titration 2025-06-03

Tuesday14 messages4 participantstimes are UTC
Highlights from this day
  • yyz_vial — appetite returning at the end of the week is extremely common and is not the dose failing 18:58
  • HPLC_Hank — genuine question whats your rule for when a side effect means hold rather than push 19:48
  • never_for_sale — small steps are better than big ones and the only reason people take big ones is impatience 19:59
  • HPLC_Hank — came down from a treatment dose to maintenance over about three months and it was uneventful 21:07
YV

appetite returning at the end of the week is extremely common and is not the dose failing

HH

genuine question whats your rule for when a side effect means hold rather than push

YV

if i took it 7 days late do i shift the schedule or go back to the old day

NF

small steps are better than big ones and the only reason people take big ones is impatience

🙏9
HH

sorry to jump in do you tell your prescriber you held or do you just hold

RS

nobody here can tell you what dose to be on and the ones who try get corrected

HH

the honest answer is that most of us are running protocols nobody has ever studied

HH

steady state is 5 weeks

Cited study
Semaglutide vs Liraglutide for Weight Loss in Adults with Overweight or Obesity (STEP 8)
JAMA · 2022
Weekly against daily, head to head.

if you are asking whether to go up, the fact you are asking usually means not yet

[edited]

came down from a treatment dose to maintenance over about three months and it was uneventful