vialroom

#dosing-titration 2025-06-14

Saturday19 messages4 participantstimes are UTC
Highlights from this day
  • VialBot — Reminder set. I will post here in 2 days. 13:09
  • VialBot — New independent result logged — SWB, lot H-2814, purity 99.4% (Janoshik). 13:14
  • slow.taper — a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored, i think 15:04
SL

how long did you hold at 0.25 before you moved up
i hold for two months minimum before i decide a dose has stopped doing anything

thats normal

🤝2

too early imo

i would hold

SO

update from 9 months ago: held at the same dose the whole time and still losing slowly, n of 1 obviously

VB

New independent result logged — SWB, lot H-2814, purity 99.4% (Janoshik).

SO

if the current dose is still working, going up is spending headroom you might want later

ST

stepping back down on purpose is a completely reasonable move and this channel should say so more often

a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored, i think

Cited study
Effect of Continued Weekly Semaglutide vs Placebo on Weight Loss Maintenance (STEP 4)
JAMA · 2021
The withdrawal arm. This is the trial to read before you plan to stop.
📈1

thats noise

is week 8 too early to be thinking about the next step

SO

sorry to jump in coming down from 12 to 0.25, how bad is the appetite rebound

SL

if it "stopped working after four days" that is almost never pharmacokinetics

16:52quiet.hours pinned a message to this channel