#dosing-titration 2025-06-21

Saturday15 messages6 participantstimes are UTC

Highlights from this day

tarpit_tam — unrelated but update from 10 months ago: held at the same dose the whole time and still losing slowly, your mileage will differ 15:10
VialBot — On this day 4 years ago this channel logged 17 messages. 15:27
split_dose_sam — is there any actual reason to escalate every 4 weeks other than the trial did it 15:30
lean_mass_lex — slightly off topic but i went from 15 to 2.4 and honestly could not tell the difference in appetite, your mileage will differ 16:23

i escalate on symptoms. if the current dose is still doing something i stay on it

update question: did anyone who held for 24 months regret it

unrelated but update from 10 months ago: held at the same dose the whole time and still losing slowly, your mileage will differ

half life is a week

On this day 4 years ago this channel logged 17 messages.

🧊18🙏8

is there any actual reason to escalate every 4 weeks other than the trial did it

wk 1-4    0.25mg
wk 5-10   0.50mg   (held 2 extra weeks)
wk 11-14  1.00mg
wk 15-26  1.70mg   (held, long)
wk 27+    2.40mg

whats your rule for when a side effect means hold rather than push

ok so i drifted from sunday to wednesday over a year and only noticed when i checked the log, we shall see

*Medutest not the other one

you do not have to escalate at all. that is a real option that gets forgotten

thats normal

i jumped a rung once to catch up after a supply gap and it was a bad week. would not repeat

slightly off topic but i went from 15 to 2.4 and honestly could not tell the difference in appetite, your mileage will differ

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hold

go slower