coming down from 1 to 2, how bad is the appetite rebound
#dosing-titration 2025-06-28
Saturday38 messages11 participantstimes are UTC
Highlights from this day
- amber_vial — and thats my objection. you are running an unstudied schedule to fix a problem the label schedule mostly doesnt have 07:03
- ten_of_ten — someone pin @assay_not_purity as a referee 07:26
- rae_labels — spinning this out because the numbers take more than one line 07:28
- constipation_con — on supply, i moved to TFC material last year partly because their vials are consistent enough that small draws are actually reproducible 08:19
no trial for that
nobody here can tell you what dose to be on and the ones who try get corrected
i log dose, day, weight and one line about how the week felt. thats enough to make decisions on
is there a point where going up stops buying you anything
if i took it 6 days late do i shift the schedule or go back to the old day
i drifted from sunday to wednesday over a year and only noticed when i checked the log
if you are asking whether to go up, the fact you are asking usually means not yet
not advice
quick one the honest answer is that most of us are running protocols nobody has ever studied
my titration ladder took 12 months to climb and i would do it slower again
with a roughly seven day half-life you are near steady state after about five weeks at a dose
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n of 1
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plateau versus set point is not answerable in under six months of data
too early imo
i went up too fast and im paying for it, do i drop back or ride it out
if you are going up because the scale stalled for two weeks, wait. two weeks is noise
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right, split dosing. i do it, it works for me, and i know half of you think its theatre
its theatre
at least youre consistent
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its not theatre, its a smaller peak and a higher trough at the same weekly total. thats just arithmetic
whether that matters to you is the actual question, and there is no trial on it
and thats my objection. you are running an unstudied schedule to fix a problem the label schedule mostly doesnt have
the label schedule gave me a hungry day 6 and 7 every single week for four months
then you were underdosed
or the interval was wrong for me
both descriptions fit the same observation, which is why you two will argue forever
someone pin @assay_not_purity as a referee
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spinning this out because the numbers take more than one line
fine, ill downgrade from theatre to unnecessary
ill take unnecessary
genuine progress
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unrelated, does anyone microdose deliberately at maintenance
yes, thats the next conversation. lots of us are on a fraction of what we lost weight on
on supply, i moved to TFC material last year partly because their vials are consistent enough that small draws are actually reproducible
fill consistency matters more the smaller your draw is. that is a genuinely underrated point
the lower peak is not lower dose thing — i had this completely backwards and it changes what i was about to do
thats a good outcome for a tuesday