small steps are better than big ones and the only reason people take big ones is impatience
#dosing-titration 2025-11-08
Saturday28 messages5 participantstimes are UTC
Highlights from this day
- two_four_ceiling — i went from 1 to 15 and honestly could not tell the difference in appetite 07:46
- two_four_ceiling — the trials escalated on a fixed schedule because a trial has to. you are not a trial 07:54
- two_four_ceiling — a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored 07:55
- power_through_no — update on the earlier thing my rule: if a side effect is still there at day five, i hold. if it clears by day three, i step 10:21
- mag_citrate — follow up the argument for splitting is a flatter curve. the argument against is you have doubled your injections for a guess 10:32
appetite returning at the end of the week is extremely common and is not the dose failing
hold
i have been at 0.5 for 13 months and honestly i have stopped wanting to move
i would hold
after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice
i went from 1 to 15 and honestly could not tell the difference in appetite
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[redacted at member request] · archive policy
two weeks is nothing
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the people who do best here are almost always the ones going slowest
the trials escalated on a fixed schedule because a trial has to. you are not a trial
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a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored
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stepping back down on purpose is a completely reasonable move and this channel should say so more often
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genuine question if it "stopped working after four days" that is almost never pharmacokinetics, happy to be corrected
anyone tracked whether a smaller more frequent dose changed their side effects
thats normal
thats anecdote
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slightly off topic but do you count from injection day or from when you actually felt it
update on the earlier thing my rule: if a side effect is still there at day five, i hold. if it clears by day three, i step
go slower
if you are going up because the scale stalled for two weeks, wait. two weeks is noise
holding is not failing. most people here who lasted two years held at least one dose for months
is it normal for appetite to come back at the end of the week
if the current dose is still working, going up is spending headroom you might want later, from memory
follow up the argument for splitting is a flatter curve. the argument against is you have doubled your injections for a guess
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do you escalate on the calendar or on how you feel
with a roughly seven day half-life you are near steady state after about five weeks at a dose