vialroom

#dosing-titration 2025-11-17

Monday19 messages6 participantstimes are UTC
Highlights from this day
  • two_four_ceiling — if i hold at 5 indefinitely am i losing anything 14:41
  • nine_nine_one — split dosing has no trial behind it. people here do it and report on it, thats all 16:26
  • two_four_ceiling — what does the room think about jumping a rung to catch up 16:55
  • two_four_ceiling — how do you tell a plateau from just being at your set point 18:09
VL

appetite returning at the end of the week is extremely common and is not the dose failing

VL

if it "stopped working after four days" that is almost never pharmacokinetics

👀2💀1📈1

i drifted from sunday to wednesday over a year and only noticed when i checked the log, for what its worth

VL

you do not have to escalate at all. that is a real option that gets forgotten

NN

split dosing has no trial behind it. people here do it and report on it, thats all

❤️3🤝3👍6
MM

i went from 1 to 7.5 and honestly could not tell the difference in appetite

*Medutest not the other one

no trial for that

🧊1👀4🙏18

thats noise

not advice

🙏10

small steps are better than big ones and the only reason people take big ones is impatience

TF

sorry to jump in after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice

if you are asking whether to go up, the fact you are asking usually means not yet

EE

follow up coming down from 12 to 10, how bad is the appetite rebound
the honest answer is that most of us are running protocols nobody has ever studied