go slower
#dosing-titration 2026-01-05
Monday21 messages3 participantstimes are UTC
Highlights from this day
- nhs_pathway_nell — if the current dose is still working, going up is spending headroom you might want later 17:50
- nhs_pathway_nell — genuine question i log dose, day, weight and one line about how the week felt. thats enough to make decisions on 17:52
- nhs_pathway_nell — genuine question the trials escalated on a fixed schedule because a trial has to. you are not a trial, from memory i went to the top of the ladder, felt no better… 17:54
half life is a week
thats normal
[edited]the ladder in the trials is a starting point, not a schedule you owe anyone, still working it out
how much does the last dose still matter 2 days later
update from 25 months ago: held at the same dose the whole time and still losing slowly
i escalate on symptoms. if the current dose is still doing something i stay on it
if you are asking whether to go up, the fact you are asking usually means not yet
*PeptideMeter not the other one
small steps are better than big ones and the only reason people take big ones is impatience
has anyone gone up and then straight back down and been glad they tried
i jumped a rung once to catch up after a supply gap and it was a bad week. would not repeat
while im here how do you decide between holding and stepping when both feel wrong
i log dose, day, weight and one line about how the week felt. thats enough to make decisions on
*week 11 not week 2
if i took it 9 days late do i shift the schedule or go back to the old day
came down from a treatment dose to maintenance over about three months and it was uneventful, i think
with a roughly seven day half-life you are near steady state after about five weeks at a dose
is week 22 too early to be thinking about the next step
if the current dose is still working, going up is spending headroom you might want later
❤️7🧪13🤝7
genuine question i log dose, day, weight and one line about how the week felt. thats enough to make decisions on
📉7🎉3
genuine question the trials escalated on a fixed schedule because a trial has to. you are not a trial, from memory
i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else
🧪12✅2
is there a trial anywhere that studied twice weekly, or is it all anecdote