whats the longest anyone has stayed on one dose
#dosing-titration 2026-01-22
i have been at 2.4 for 20 months and honestly i have stopped wanting to move
split dosing has no trial behind it. people here do it and report on it, thats all
thats anecdote
pick a day and stick to it
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
for the archive do you escalate on the calendar or on how you feel
not advice
[edited]Reminder set. I will post here in 8 days.
whats a sensible maintenance dose after a year at treatment dose
too early imo
thats noise
steady state is 5 weeks
i hold for two months minimum before i decide a dose has stopped doing anything
my dose day has drifted 3 days later over 13 months, does it matter
no trial for that
stepping back down on purpose is a completely reasonable move and this channel should say so more often
a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored
i jumped a rung once to catch up after a supply gap and it was a bad week. would not repeat, thats just me
i log dose, day, weight and one line about how the week felt. thats enough to make decisions on
if i took it 2 days late do i shift the schedule or go back to the old day
holding is not failing. most people here who lasted two years held at least one dose for months
the honest answer is that most of us are running protocols nobody has ever studied
is week 22 too early to be thinking about the next step
follow up whats the smallest step anyone has managed between doses
you do not have to escalate at all. that is a real option that gets forgotten, thats one data point
n of 1