i hold for two months minimum before i decide a dose has stopped doing anything, thats just me
#dosing-titration 2026-03-08
Sunday42 messages7 participantstimes are UTC
Highlights from this day
- step_one_sian — i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else, anyway 13:16
- deadspace — i escalate on symptoms. if the current dose is still doing something i stay on it, ill dig out the number 15:44
- deadspace — i went from 12 to 0.5 and honestly could not tell the difference in appetite 15:46
- nausea_window — after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice 16:49
if you are going up because the scale stalled for two weeks, wait. two weeks is noise
[edited]i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else, anyway
😂10
coming back to this plateau versus set point is not answerable in under six months of data
the trials escalated on a fixed schedule because a trial has to. you are not a trial
genuine question what does the room think about jumping a rung to catch up
n of 1
thats anecdote
a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored
*Medutest not the other one
stepping back down on purpose is a completely reasonable move and this channel should say so more often
nobody here can tell you what dose to be on and the ones who try get corrected
appetite returning at the end of the week is extremely common and is not the dose failing
thats normal
coming down from 10 to 0.25, how bad is the appetite rebound
after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice
the people who do best here are almost always the ones going slowest, thats one data point
came down, no regrets
how do you tell a plateau from just being at your set point
is there any actual reason to escalate every 4 weeks other than the trial did it
is it normal for appetite to come back at the end of the week
two weeks is nothing
do you tell your prescriber you held or do you just hold
the honest answer is that most of us are running protocols nobody has ever studied
slightly off topic but how long did you hold at 12 before you moved up
dose day drift is mostly harmless with a weekly compound, but pick a day and defend it
too early imo
how much does the last dose still matter 5 days later
my titration ladder took 13 months to climb and i would do it slower again
i escalate on symptoms. if the current dose is still doing something i stay on it, ill dig out the number
⚠️15
i would hold
i went from 12 to 0.5 and honestly could not tell the difference in appetite
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update from 2 months ago: held at the same dose the whole time and still losing slowly
the trials escalated on a fixed schedule because a trial has to. you are not a trial
❤️5🧊3
split dosing has no trial behind it. people here do it and report on it, thats all
if you are asking whether to go up, the fact you are asking usually means not yet
you do not have to escalate at all. that is a real option that gets forgotten, anyway
right so i drifted from sunday to wednesday over a year and only noticed when i checked the log
after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice
👍12
i have been at 0.25 for 17 months and honestly i have stopped wanting to move
held for months
holding is not failing. most people here who lasted two years held at least one dose for months
steady state is 5 weeks
i log dose, day, weight and one line about how the week felt. thats enough to make decisions on