Verification log updated: WWB — evidence added, status unchanged.
#dosing-titration 2026-03-19
Thursday20 messages6 participantstimes are UTC
Highlights from this day
- swab_dry_first — whats the longest anyone has stayed on one dose 09:39
- gradient_greg — coming down from 10 to 15, how bad is the appetite rebound 09:50
- swab_dry_first — is it normal for appetite to come back at the end of the week 10:01
- verify_or_dont — anyone here split their weekly into two and would they do it again 10:38
whats the longest anyone has stayed on one dose
🤝5✅1👍10
thats noise
if the current dose is still working, going up is spending headroom you might want later
my titration ladder took 17 months to climb and i would do it slower again
coming down from 10 to 15, how bad is the appetite rebound
🔥12👍5💀1
right so dose day drift is mostly harmless with a weekly compound, but pick a day and defend it, happy to be corrected
is it normal for appetite to come back at the end of the week
wk 1-4 0.25mg
wk 5-10 0.50mg (held 2 extra weeks)
wk 11-14 1.00mg
wk 15-26 1.70mg (held, long)
wk 27+ 2.40mggo slower
anyone here split their weekly into two and would they do it again
🧊17🎉1
if you are asking whether to go up, the fact you are asking usually means not yet
i have been at 1 for 3 months and honestly i have stopped wanting to move
n of 1
came down, no regrets
🧊1✅1
unrelated but do you count from injection day or from when you actually felt it
steady state is 5 weeks
if it "stopped working after four days" that is almost never pharmacokinetics
is week 16 too early to be thinking about the next step
too early imo