not advice
#dosing-titration 2026-06-01
Monday25 messages5 participantstimes are UTC
Highlights from this day
- triple_ag_tom — a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored the honest answer is that most of us are running… 01:34
- meal_prep_mick — if i took it 5 days late do i shift the schedule or go back to the old day 02:51
- triple_ag_tom — the people who do best here are almost always the ones going slowest 04:11
- VialBot — On this day 4 years ago this channel logged 91 messages. 05:09
a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored
the honest answer is that most of us are running protocols nobody has ever studied
if you are asking whether to go up, the fact you are asking usually means not yet
the trials escalated on a fixed schedule because a trial has to. you are not a trial
i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else
coming down from 10 to 1, how bad is the appetite rebound
i would hold
if i took it 5 days late do i shift the schedule or go back to the old day
💀3📉9
update from 3 months ago: held at the same dose the whole time and still losing slowly
after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice
unrelated but i went up too fast and im paying for it, do i drop back or ride it out
the people who do best here are almost always the ones going slowest
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
my rule: if a side effect is still there at day five, i hold. if it clears by day three, i step
On this day 4 years ago this channel logged 91 messages.
appetite returning at the end of the week is extremely common and is not the dose failing, not advice obviously
thats normal
pick a day and stick to it
[edited]ok so if i hold at 2 indefinitely am i losing anything
stepping back down on purpose is a completely reasonable move and this channel should say so more often
right so whats your rule for when a side effect means hold rather than push
*VendorInvestigate not the other one
thats noise
holding is not failing. most people here who lasted two years held at least one dose for months
i have been at 0.25 for 16 months and honestly i have stopped wanting to move
while im here with a roughly seven day half-life you are near steady state after about five weeks at a dose