sorry to jump in the people who do best here are almost always the ones going slowest
#dosing-titration 2026-06-09
Tuesday19 messages7 participantstimes are UTC
Highlights from this day
- marrow.mod — i log dose, day, weight and one line about how the week felt. thats enough to make decisions on 12:27
- VialBot — Channel stats, last 30 days: 102 messages from 21 members. 12:28
- panel_before_after — has anyone gone up and then straight back down and been glad they tried 13:28
- panel_before_after — sorry to jump in my titration ladder took 23 months to climb and i would do it slower again, still working it out 13:48
- two_four_ceiling — with a roughly seven day half-life you are near steady state after about five weeks at a dose 15:28
small steps are better than big ones and the only reason people take big ones is impatience
came down from a treatment dose to maintenance over about three months and it was uneventful
i log dose, day, weight and one line about how the week felt. thats enough to make decisions on
Channel stats, last 30 days: 102 messages from 21 members.
i went from 1 to 2.4 and honestly could not tell the difference in appetite
steady state is 5 weeks
📈16
my dose day has drifted 8 days later over 16 months, does it matter
i have been at 5 for 1 months and honestly i have stopped wanting to move
has anyone gone up and then straight back down and been glad they tried
✅7
sorry to jump in my titration ladder took 23 months to climb and i would do it slower again, still working it out
[edited]the honest answer is that most of us are running protocols nobody has ever studied
with a roughly seven day half-life you are near steady state after about five weeks at a dose
follow up i escalate on symptoms. if the current dose is still doing something i stay on it
whats the smallest step anyone has managed between doses
hold
held for months
i drifted from sunday to wednesday over a year and only noticed when i checked the log
half life is a week