#lab-requests 2025-08-12

Tuesday45 messages12 participantstimes are UTC

Highlights from this day

tail_factor — it is the cheapest possible defence against us and we have no way to detect it 13:50
blind_submit — where the money has actually gone, nine rounds in 14:27
blind_submit — that note is the whole ethic of this channel honestly 15:14

yyz_vial 10:38

in for one

HPLC_Hanklab10:41

publish the raw

ten_percent_off 10:44

code not name

ten_percent_off 10:55

sorry to jump in a code and a lot number on the syringe in permanent marker. that is the whole labelling requirement

add a standard

can i add a second lot to the same submission

HPLC_Hanklab10:58

we have never had a lab mix up a sample. we have had members mix up their own labelling twice
i keep half the sample back so there is something to send if the first one goes missing

yyz_vial 11:24

declare it as an analytical reference sample with a low value. that is what it is

[edited]

endotoxin_edlab11:28

slightly off topic but we do not help with wording beyond that and the mods are strict about it, i could be wrong

endotoxin_edlab11:54

follow up the queue is posted and updated. if your code is not on it, it did not arrive

code  compound      submitted   status
R-01  semaglutide   2026-02-14  reported
R-02  tirzepatide   2026-02-14  reported
R-03  retatrutide   2026-02-16  in queue
R-04  reference std 2026-02-16  reported

fridge_thermo 12:16

chain of custody in hobby testing is weak and we say so in every writeup

🎉8📉2

fridge_thermo 12:42

we publish the raw report. summaries hide the thing you needed to see

ten_percent_off can i add a second lot to the same submission

nausea_window 12:43

VendorInvestigate has been the fastest for us. VendorInvestigate has been the most detailed. those are not the same lab

💀4

HPLC_Hanklab13:11

quantity is the test worth paying for. purity is usually fine and fill usually is not

do not send your only vial. that has happened twice and both times it hurt

⚠️18

yyz_vial 13:13

anyone want to co-fund a quantity test on a lot i already own

13:19lurker_lu joined

lurker_lu 13:21

reading back through nine rounds of results and honestly it seems rigorous. is there a catch

tail_factorlab13:22

there are several and they are worth stating plainly because the alternative is people quoting our numbers as if they were regulatory data

one: we cannot verify the vial came from the vendor named. the submitter says so and we believe them.
two: we cannot verify storage before submission.
three: the sample is one vial from one box from one order.
four: whoever holds the blinding key could break it and nobody would know.
five: we choose what to test, and we choose when we are suspicious

blind_submit 13:26

and six, which is mine: we publish everything, so a vendor can read our methodology and prepare for it

lurker_lu 13:27

could they actually do that

ferritin_fay 13:30

sending a good vial to a known frequent tester is not hard and costs almost nothing

tail_factorlab13:50

it is the cheapest possible defence against us and we have no way to detect it

😬14

vialkeeperfounder14:18

we decided in 2024 to publish anyway. an open method with known weaknesses beats a secret one people cannot check

lurker_lu 14:21

who decides which compound gets priority

blind_submit 14:24

whoever pays, mostly. we vote but the funding decides

ferrous_ashmod14:26

which is a bias nobody mentions. the compounds with enthusiastic buyers get tested and the quiet ones do not

blind_submit 14:27

where the money has actually gone, nine rounds in

Compound	Purity results on file	Content results	Gap
semaglutide	31	14	content thin but usable
tirzepatide	22	9	content thin
retatrutide	6	1	essentially unknown
cagrilintide	4	0	no content data at all
everything else	11	2	anecdote

📊13😐6

lurker_lu 14:28

cagrilintide with zero content results and people are still dosing it

tail_factorlab15:02

people dose plenty of things with no content data. that is a choice they make and it is not mine to police

ferrous_ashmod15:09

and it stays that way in here. we test, we publish, we do not prescribe

ferritin_fay 15:12

the clinical data on the combination is not the same thing as data on your vial either

this is the actual molecule everyone is reasoning from

Cited study

Tirzepatide Once Weekly for the Treatment of Obesity (SURMOUNT-1)

New England Journal of Medicine · 2022

the trial used a known product at a known dose. our results describe powders of unknown provenance. do not merge the two in your head

blind_submit 15:14

that note is the whole ethic of this channel honestly

💯17

lurker_lu 15:17

so what would make hobby testing actually strong

tail_factorlab15:32

buying the vials ourselves from a fresh account, with money nobody in the group can trace to us, and sending them blind.
we have costed it. it roughly triples the price per data point.
nobody has funded a full round that way

ferritin_fay 15:44

we did one slot like that once, JEEP, and it came back the same as the submitted vials

tail_factorlab15:45

n of one. reassuring and inconclusive

blind_submit 15:46

the phrase reassuring and inconclusive describes about 80% of this archive

lurker_lu 15:48

and Kerui, Homopeptide, the smaller ones, will they ever get tested

blind_submit whoever pays, mostly. we vote but the funding decides

blind_submit 15:51

only if someone with a vial and sixty quid decides to. that is the entire mechanism

ferrous_ashmod16:00