vialroom

#maintenance 2025-09-06

Saturday49 messages10 participantstimes are UTC
Highlights from this day
  • VialBot — On this day 3 years ago this channel logged 52 messages. 15:20
  • food_noise_off — how do people handle a two week holiday at a maintenance dose 16:13
  • spreadsheet_stu — coming down too fast was my mistake. top rung to the bottom rung inside a month and it was a bad month 16:21
  • pinch_not_stretch — nobody here can tell you whether to stop. we can tell you what happened to us when we did 16:23
  • VialBot — Verification log updated: Homopeptide — evidence added, status unchanged. 17:20
PP

the maintenance conversation barely existed in here two years ago and now it is half the channel

harder than losing

PP

update from 20 months ago: still at maintenance, still boring, which was always the goal
if you find maintenance harder than the losing part you are in the majority in this room

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PP

appetite came back over about three weeks after i reduced, not all at once, which is what i had braced for, ymmv

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does anyone lift specifically to hold onto muscle now that theyre maintaining

PP

i stayed at treatment dose for four months past goal and then came down slowly. that order was right for me

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FN

appetite returning is not the drug failing, it is the drug doing less because you are taking less of it

VB

On this day 3 years ago this channel logged 52 messages.

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VB

Digest for the week of 2025-03-03 has been published.

FN

sorry to jump in two or three kilos up and down is normal fluctuation. ten is a different conversation

FN

the honest answer to is this forever is that nobody knows and the drug only works while you are taking it, thats one data point

how do people handle a two week holiday at a maintenance dose

Cited study
Effect of Continued Weekly Semaglutide vs Placebo on Weight Loss Maintenance (STEP 4)
JAMA · 2021
The withdrawal arm. This is the trial to read before you plan to stop.
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the food noise came back at the lower dose, does it settle again

SS

slightly off topic but food noise coming back at a lower dose settled again after about four weeks for me, n of 1 obviously

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coming down too fast was my mistake. top rung to the bottom rung inside a month and it was a bad month

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PN

nobody here can tell you whether to stop. we can tell you what happened to us when we did

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PN

everybody i have seen stop and hold it did something else as well, without exception in my time here, not advice obviously

SS

genuine question is there any trial data at all on a lower frequency schedule

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PN

FLOW is the stopping one. weight came back on for most people once the drug stopped. that is the finding, not an opinion

TO

i went to every ten days at a low dose and it held for me. n of 1, and i keep saying that out loud, ill dig out the number

TO

im holding at 0.5 for maintenance and wondering whether i should be lower

maintenance is harder than losing because there is no number going down to keep you interested

PN

the muscle question is the one i wish i had taken seriously at month two instead of month twelve

i dropped from 2 to 1.7 for maintenance and held steady for fourteen months, i think

PP

protein went up during maintenance for me rather than down, which was completely counterintuitive

VB

Verification log updated: Homopeptide — evidence added, status unchanged.

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FI

cost did not drop at maintenance for me because i went to a lower dose from the same vial and just used it slower

MP

did your maintenance dose end up higher or lower than you expected it to

MP

regain after stopping is the expected outcome, which is a horrible sentence and also what the data says, your mileage will differ

whats your rule for when a fluctuation becomes a regain

OO

a 10mg vial at a 2mg maintenance dose is five weeks of doses, so my monthly cost roughly halved

OO

dropping to a maintenance dose was uneventful for me and completely miserable for somebody i talk to weekly

FN

if i go back up after regain does it work the same the second time
my range is 46 and i stopped calling anything inside that a regain

OO

i lift twice a week specifically because losing fast without it cost me more than i was willing to lose

FN

i tried to come down and could not hold it, went back to treatment dose, and stopped apologising for it

OO

i think about it the way i think about my blood pressure tablet, and that framing helped me more than anything else

lower frequency maintenance is genuinely unstudied. anybody telling you it is proven is making that up