vialroom

#oral-glp1 2024-12-11

Wednesday20 messages5 participantstimes are UTC
Highlights from this day
  • septum_sal — i was wrong about the water amount, i was using a sip and it needs a lot more than that, happy to be corrected 22:33
  • tenpence — the oral mg number is bigger because almost none of it gets in, thats the entire reason orforglipron is a small molecule rather than a peptide, which is why the… 22:49
  • oasis_ola — i do 6am with water and eat at 7, thats been my routine for 23 months, not advice obviously 23:27
  • verify_or_dont — the fasting rule cost me my breakfast routine and thats the real reason people quit the oral switched from injectable to oral, lost some of the effect, switched back… 23:28
SS

i was wrong about the water amount, i was using a sip and it needs a lot more than that, happy to be corrected

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the fasting window is the difference between a dose and a very expensive tablet, ymmv

thirty minutes, no cheating

[edited]
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changed my mind on the plain water rule after reading how SNAC works, its not a formality

1
TE

the 30 minutes starts when you swallow it, and i set a timer because i cannot be trusted

is the plain water rule actually load bearing or is it a formality
tea also does not count, in case anyone was hoping

the oral mg number is bigger because almost none of it gets in, thats the entire reason
orforglipron is a small molecule rather than a peptide, which is why the fasting conditions differ

weights-monthly.csv
872 rows · not retained in the public archive
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slightly off topic but nobody should copy my morning routine, but the timer is the bit i would keep

technique probably

VB

Batch lookup B-0329: 6 independent reports on file, earliest 2024-08-03.

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OO

absorption is the variable, not the molecule. same tablet, different morning, different result

VO

took mine with breakfast once by accident and that week was a write off

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VO

is the non peptide thing why orforglipron doesnt need the fasting rules
the inconsistency is mostly technique and admitting that took me about a year

*VendorInvestigate not the other one

OO

i do 6am with water and eat at 7, thats been my routine for 23 months, not advice obviously

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VO

the fasting rule cost me my breakfast routine and thats the real reason people quit the oral
switched from injectable to oral, lost some of the effect, switched back after 5 months

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VB

Archive lookup: verify_or_dont first appears in this channel on 2024-10-01.

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OO

the oral disappointed me on the mornings i couldnt manage 30 minutes fasted, which was most of them