my weekly log on oral is noisier than my injectable log ever was, same scales same mornings
#oral-glp1 2025-03-06
Thursday31 messages8 participantstimes are UTC
Highlights from this day
- gip_glp_gil — switched from injectable to oral, lost some of the effect, switched back after 1 months 21:41
- VialBot — Verification log updated: Homopeptide — evidence added, status unchanged. 21:45
- meniscus_mel — the non peptide agents dose daily without the water ritual, thats the practical difference 22:01
- two_four_ceiling — i keep the tablet by the kettle so i take it before i think about food 22:36
- two_four_ceiling — oral was easier on my gut than injecting at what felt like a similar effect, which surprised me 22:41
switched from injectable to oral, lost some of the effect, switched back after 1 months
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Verification log updated: Homopeptide — evidence added, status unchanged.
genuine question the 30 minutes starts when you swallow it, and i set a timer because i cannot be trusted
fasted every morning
lost 41kg over 17 months on oral, slower than my injectable stretch, i stuck with it anyway
orforglipron is a small molecule rather than a peptide, which is why the fasting conditions differ
SNAC does the work
*PeptideMeter not the other one
the non peptide agents dose daily without the water ritual, thats the practical difference
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while im here how long before the oral did anything measurable for you
took 3 weeks before i saw anything on oral, roughly twice what the injection took me
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anyone switched from injectable to oral and kept the same effect
whats the bioavailability actually like, i keep seeing about one percent
i keep the tablet by the kettle so i take it before i think about food
is the plain water rule actually load bearing or is it a formality
went back to injecting because the morning routine was too fragile around shift work
not a peptide
coffee doesnt count
did anyone find the oral easier on the gut than the injection
is the non peptide thing why orforglipron doesnt need the fasting rules
i keep the tablet by the kettle so i take it before i think about food
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the fasting rule cost me my breakfast routine and thats the real reason people quit the oral
went back to injecting
oral was easier on my gut than injecting at what felt like a similar effect, which surprised me
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Recon calculator: 10mg in 1ml = 10mg/ml.
anyone dosing oral because of a needle problem rather than preference
genuine question i use it because needles are a genuine problem for me, not because i think its better
does SNAC do anything other than get it through the stomach
the inconsistency is mostly technique and admitting that took me about a year
my oral results were inconsistent week to week and i eventually decided it was me, not the tablet