vialroom

#oral-glp1 2025-07-20

Sunday29 messages5 participantstimes are UTC
Highlights from this day
  • reship_rita — PIONEER was the original oral semaglutide programme and OASIS looked at the higher oral doses 17:06
  • unsolicited_dm — why is the oral dose in mg so much bigger than the injectable one 17:43
  • unsolicited_dm — i keep the tablet by the kettle so i take it before i think about food 18:04
  • gip_glp_gil — i said 4 months ago that my oral results were random, they got consistent once i fixed the water 19:06
PP

splitting a dose made the absorption problem worse rather than better in my own log

PP

follow up did OASIS use the same fasting conditions as the earlier work
the fasting rule cost me my breakfast routine and thats the real reason people quit the oral

i use it because needles are a genuine problem for me, not because i think its better, thats one data point

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PP

anyone tracking whether their oral results line up week to week

went back to injecting

PIONEER was the original oral semaglutide programme and OASIS looked at the higher oral doses

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UD

took 8 weeks before i saw anything on oral, roughly twice what the injection took me, i think

my oral results were inconsistent week to week and i eventually decided it was me, not the tablet

does taking it with any food at all just waste the dose

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UD

why is the oral dose in mg so much bigger than the injectable one

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for the archive how strict is the 30 minute wait before food for people here

*Medutest not the other one

whats the bioavailability actually like, i keep seeing about one percent

i keep the tablet by the kettle so i take it before i think about food

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PP

the inconsistency is mostly technique and admitting that took me about a year

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GG

i said 4 months ago that my oral results were random, they got consistent once i fixed the water

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SA

the fasting window is the difference between a dose and a very expensive tablet, not advice obviously
went back to injecting because the morning routine was too fragile around shift work

PP

nobody should copy my morning routine, but the timer is the bit i would keep, n of 1 obviously

SA

my weekly log on oral is noisier than my injectable log ever was, same scales same mornings