SNAC raises the local pH and protects it long enough to cross, thats its whole job
#oral-glp1 2025-08-27
Wednesday26 messages6 participantstimes are UTC
Highlights from this day
- sulphur_burp — OASIS ran under the same sort of fasting conditions, thats not the variable between the two, for what its worth 23:04
- orfor_watch — i keep the tablet by the kettle so i take it before i think about food, i think 23:13
- orfor_watch — switched from injectable to oral, lost some of the effect, switched back after 19 months 23:15
plain water only, about half a glass, then nothing for 30 minutes. i follow it exactly
i use it because needles are a genuine problem for me, not because i think its better
ruined my breakfast
coffee doesnt count
lost 23kg over 7 months on oral, slower than my injectable stretch, i stuck with it anyway
not a peptide
thirty minutes, no cheating
plain water only
SNAC does the work
OASIS ran under the same sort of fasting conditions, thats not the variable between the two, for what its worth
right so nobody should copy my morning routine, but the timer is the bit i would keep, ymmv
how much water exactly, is it a small sip or half a glass
i keep the tablet by the kettle so i take it before i think about food, i think
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switched from injectable to oral, lost some of the effect, switched back after 19 months
coa-a-2418.pdf
1 page · 655 KB · not retained in the public archive
PIONEER not OASIS
about one percent
medutest-report-a-2601.pdf
3 pages · 382 KB · not retained in the public archive
coffee is not plain water. i tried it for a month and my results got worse
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my oral results were inconsistent week to week and i eventually decided it was me, not the tablet
technique probably
genuine question whats the bioavailability actually like, i keep seeing about one percent
i was wrong about the water amount, i was using a sip and it needs a lot more than that
the inconsistency is mostly technique and admitting that took me about a year
follow up oral was easier on my gut than injecting at what felt like a similar effect, which surprised me
my weekly log on oral is noisier than my injectable log ever was, same scales same mornings
is the non peptide thing why orforglipron doesnt need the fasting rules