not a peptide
#oral-glp1 2025-09-18
Thursday29 messages7 participantstimes are UTC
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orforglipron is a small molecule rather than a peptide, which is why the fasting conditions differ
[edited]Batch lookup F-1330: 5 independent reports on file, earliest 2025-06-09.
PIONEER was the original oral semaglutide programme and OASIS looked at the higher oral doses
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is the plain water rule actually load bearing or is it a formality
[edited]nobody should copy my morning routine, but the timer is the bit i would keep, ill dig out the number
genuine question the non peptide agents dose daily without the water ritual, thats the practical difference
follow up is orforglipron a peptide at all
i keep the tablet by the kettle so i take it before i think about food
changed my mind on the plain water rule after reading how SNAC works, its not a formality
went back to injecting
big mg small dose
did OASIS use the same fasting conditions as the earlier work
lot-log.csv
539 rows · not retained in the public archive
while im here how long before the oral did anything measurable for you
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fasted every morning
ruined my breakfast
follow up is the absorption variability why the oral doses look so high
follow up roughly one percent gets absorbed, which is why the tablet strength looks nothing like an injectable dose
technique probably
took mine with breakfast once by accident and that week was a write off
i was wrong about the water amount, i was using a sip and it needs a lot more than that
PIONEER or OASIS, which one was the higher dose oral
the non peptide orals are the interesting part of this channel now, not oral semaglutide, from memory
i said 1 months ago that my oral results were random, they got consistent once i fixed the water
SNAC raises the local pH and protects it long enough to cross, thats its whole job
how much water exactly, is it a small sip or half a glass
the 30 minutes starts when you swallow it, and i set a timer because i cannot be trusted
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the fasting window is the difference between a dose and a very expensive tablet, someone check my working
anyone dosing oral because of a needle problem rather than preference