plain water only, about half a glass, then nothing for 30 minutes. i follow it exactly
#oral-glp1 2026-03-22
Sunday56 messages11 participantstimes are UTC
Highlights from this day
- provincial_pat — OASIS ran under the same sort of fasting conditions, thats not the variable between the two 22:26
- truncation_tru — unrelated but my weekly log on oral is noisier than my injectable log ever was, same scales same mornings 22:39
- cleo_tests — splitting a dose made the absorption problem worse rather than better in my own log 22:56
switched from injectable to oral, lost some of the effect, switched back after 3 months
fridge-temps.csv
244 rows · not retained in the public archive
not a peptide
unrelated but the fasting window is the difference between a dose and a very expensive tablet
while im here i use it because needles are a genuine problem for me, not because i think its better
thirty minutes, no cheating
did anyone get consistent results on the oral or is it always patchy
the non peptide agents dose daily without the water ritual, thats the practical difference
splitting a dose made the absorption problem worse rather than better in my own log
oral was easier on my gut than injecting at what felt like a similar effect, which surprised me
fridge-temps.csv
933 rows · not retained in the public archive
does coffee count as plain water, asking for obvious reasons
nobody should copy my morning routine, but the timer is the bit i would keep
the non peptide orals are the interesting part of this channel now, not oral semaglutide
PIONEER or OASIS, which one was the higher dose oral
took 12 weeks before i saw anything on oral, roughly twice what the injection took me
fasted every morning
the inconsistency is mostly technique and admitting that took me about a year
vat_on_importunrelated but the fasting window is the difference between a dose and a very expensive…
OASIS ran under the same sort of fasting conditions, thats not the variable between the two
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about one percent
why does the same tablet do different things week to week
while im here the 30 minutes starts when you swallow it, and i set a timer because i cannot be trusted
ruined my breakfast
PIONEER not OASIS
ok so changed my mind on the plain water rule after reading how SNAC works, its not a formality, for what its worth
is there any point splitting an oral dose
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unrelated but my weekly log on oral is noisier than my injectable log ever was, same scales same mornings
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quick one is the absorption variability why the oral doses look so high
technique probably
follow up my oral results were inconsistent week to week and i eventually decided it was me, not the tablet, happy to be corrected
*week 3 not week 5
quick one anyone dosing oral because of a needle problem rather than preference
roughly one percent gets absorbed, which is why the tablet strength looks nothing like an injectable dose
plain water only
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how much water exactly, is it a small sip or half a glass
one percent is the number people quote and the spread around it is the actual story
splitting a dose made the absorption problem worse rather than better in my own log
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back after 3 months, has anything changed on the oral side
anyone tracking whether their oral results line up week to week
*Janoshik not the other one
whats the bioavailability actually like, i keep seeing about one percent
i said 20 months ago that my oral results were random, they got consistent once i fixed the water
Reminder set. I will post here in 8 days.
i do 6am with water and eat at 7, thats been my routine for 24 months
sorry to jump in went back to injecting
coffee doesnt count
how strict is the 30 minute wait before food for people here
big mg small dose
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the fasting rule cost me my breakfast routine and thats the real reason people quit the oral
PIONEER was the original oral semaglutide programme and OASIS looked at the higher oral doses
how long before the oral did anything measurable for you
SNAC does the work
i keep the tablet by the kettle so i take it before i think about food, anyway
lost 14kg over 2 months on oral, slower than my injectable stretch, i stuck with it anyway
the oral mg number is bigger because almost none of it gets in, thats the entire reason
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did anyone find the oral easier on the gut than the injection
the oral mg number is bigger because almost none of it gets in, thats the entire reason
tea also does not count, in case anyone was hoping
coffee is not plain water. i tried it for a month and my results got worse