vialroom

#oral-glp1 2026-04-06

Monday12 messages5 participantstimes are UTC
Highlights from this day
  • snac_and_water — roughly one percent gets absorbed, which is why the tablet strength looks nothing like an injectable dose, we shall see 14:34
  • group_buy_gwen — i was wrong about the water amount, i was using a sip and it needs a lot more than that 14:35
  • split_dose_sam — the 30 minutes starts when you swallow it, and i set a timer because i cannot be trusted 15:19
  • lipase_lore — i do 6am with water and eat at 7, thats been my routine for 14 months 15:42
  • lipase_lore — changed my mind on the plain water rule after reading how SNAC works, its not a formality, still working it out 16:18

coffee doesnt count

mine was patchy too

roughly one percent gets absorbed, which is why the tablet strength looks nothing like an injectable dose, we shall see

GB

i was wrong about the water amount, i was using a sip and it needs a lot more than that

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LL

i do 6am with water and eat at 7, thats been my routine for 14 months

Cited study
Oral Semaglutide 50 mg in Adults with Overweight or Obesity (OASIS 1)
The Lancet · 2023
The high-dose oral. Absorption rules matter enormously here.

set a timer

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orforglipron is a small molecule rather than a peptide, which is why the fasting conditions differ

LL

changed my mind on the plain water rule after reading how SNAC works, its not a formality, still working it out

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