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#oral-glp1 2026-04-10

Friday13 messages5 participantstimes are UTC
Highlights from this day
  • seizure_letter — the non peptide orals are the interesting part of this channel now, not oral semaglutide 15:53
  • stopped_and_regained — roughly one percent gets absorbed, which is why the tablet strength looks nothing like an injectable dose 16:12
  • seizure_letter — OASIS ran under the same sort of fasting conditions, thats not the variable between the two 16:22
  • drawup_dee — PIONEER was the original oral semaglutide programme and OASIS looked at the higher oral doses 16:29
  • drawup_dee — the non peptide agents dose daily without the water ritual, thats the practical difference i keep the tablet by the kettle so i take it before i think about food 17:04

i use it because needles are a genuine problem for me, not because i think its better

SL

the non peptide orals are the interesting part of this channel now, not oral semaglutide

👍1

did anyone get consistent results on the oral or is it always patchy

AN

went back to injecting because the morning routine was too fragile around shift work

SA

roughly one percent gets absorbed, which is why the tablet strength looks nothing like an injectable dose

🔥1🧪1🙏1
SL

OASIS ran under the same sort of fasting conditions, thats not the variable between the two

DD

PIONEER was the original oral semaglutide programme and OASIS looked at the higher oral doses

QH

i was wrong about the water amount, i was using a sip and it needs a lot more than that

DD

does coffee count as plain water, asking for obvious reasons

the non peptide agents dose daily without the water ritual, thats the practical difference
i keep the tablet by the kettle so i take it before i think about food

how much water exactly, is it a small sip or half a glass