i was wrong about the water amount, i was using a sip and it needs a lot more than that, for what its worth
#oral-glp1 2026-05-06
Wednesday22 messages5 participantstimes are UTC
Highlights from this day
- deadspace — i was wrong about the water amount, i was using a sip and it needs a lot more than that, for what its worth 16:46
- belfast_bac — is there any point splitting an oral dose 17:11
- split_shipment — genuine question changed my mind on the plain water rule after reading how SNAC works, its not a formality 18:16
- split_shipment — the oral mg number is bigger because almost none of it gets in, thats the entire reason, happy to be corrected i use it because needles are a genuine problem for me,… 19:05
PIONEER was the original oral semaglutide programme and OASIS looked at the higher oral doses
orforglipron is a small molecule rather than a peptide, which is why the fasting conditions differ
is there any point splitting an oral dose
🧊8🧪1👀1
why is the oral dose in mg so much bigger than the injectable one
set a timer
technique probably
did anyone get consistent results on the oral or is it always patchy
quick one tea also does not count, in case anyone was hoping
fasted every morning
not a peptide
genuine question changed my mind on the plain water rule after reading how SNAC works, its not a formality
ruined my breakfast
took mine with breakfast once by accident and that week was a write off
unrelated but the non peptide orals are the interesting part of this channel now, not oral semaglutide
does the 30 minutes start from swallowing or from the water
plain water only, about half a glass, then nothing for 30 minutes. i follow it exactly
*Medutest not the other one
the oral mg number is bigger because almost none of it gets in, thats the entire reason, happy to be corrected
i use it because needles are a genuine problem for me, not because i think its better
went back to injecting
anyone tracking whether their oral results line up week to week
whats the bioavailability actually like, i keep seeing about one percent