anyone got a photo of what a properly dissolved vial looks like
#reconstitution 2026-02-21
Saturday44 messages12 participantstimes are UTC
Highlights from this day
- forty_units — right so give it 9 minutes at room temperature before you decide it has not dissolved 22:51
- forty_units — update from 13 months ago: switched to a single concentration and have not miscalculated since 22:52
- quiet.hours — quick one my rule is one concentration for everything so i never have to think about it at 7am 23:04
- VialBot — Purity check: no report on file for lot H-2814. Nothing logged either way. 23:09
- no_appetite_nia — how much do i lose to dead space with a 30G pin 23:13
check your maths
took me a year to stop over-diluting. the measurement error at 4 units is worse than the convenience, ill dig out the number
30mg in 3ml is 10mg/ml, so 5mg is 50 units. half the barrel, feels like a lot but its right
unrelated but i use bac water even for a single-use vial because it stings less, which is not the reason it exists
ok so my vial pulled the water in on its own, is that the vacuum or did i do something
if you cannot read the mark confidently, your volume is too small. redo it at a lower concentration
does it matter if i inject the bac water straight at the powder
the vacuum will pull it in. let it. fighting it is how you get a face full of aerosol
read it at eye level
temperature of the diluent does not matter. how fast you push it in does
do not add more bac water to an already reconstituted vial, you have lost track of the concentration
is the meniscus reading actually a real source of error or am i overthinking
is there any reason not to just always use 2ml
do i swirl for a specific length of time or just until its clear
genuine question gross powder mass is not net peptide. water and counterion are in that number
i was wrong about this last year: it is fine to draw cold, it just stings more going in
a 3ml syringe for the diluent and a u100 for the dose is the setup most people here end up with
*VendorInvestigate not the other one
right so give it 9 minutes at room temperature before you decide it has not dissolved
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update from 13 months ago: switched to a single concentration and have not miscalculated since
fridge-temps.csv
637 rows · not retained in the public archive
i keep a spare vial of bac water in the fridge purely so i never rush the maths
Batch lookup A-2601: 3 independent reports on file, earliest 2025-06-04.
sanity check my maths before i pin myself with something stupid
genuine question i write the mg/ml on the vial with a sharpie the moment i reconstitute it
quick one my rule is one concentration for everything so i never have to think about it at 7am
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does temperature of the bac water matter at all
Purity check: no report on file for lot H-2814. Nothing logged either way.
thats 5mg/ml
coa-b-0114.pdf
1 page · 504 KB · not retained in the public archive
how much do i lose to dead space with a 30G pin
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if the maths gives you 13.7 units, change the volume. do not try to hit 13.7
while im here i have never once regretted using a rounder number and a slightly bigger volume
update on the earlier thing lyophilised powder is far more robust than people think. it is the solution that is fragile
round numbers
i swirl for about thirty seconds and then leave it. never had one fail to dissolve
if the powder is on the stopper, tap it down before you add anything. it will still dissolve either way
write the date on
is it worth buying a 3ml syringe for the diluent or is the insulin one fine
sorry to jump in the meniscus thing is real. read it at eye level or you are guessing by a unit either way
do you draw up with the same pin you inject with
the last few units are a real loss. i accept it rather than tilting the vial and drawing air
if the powder is on the stopper, tap it down before you add anything. it will still dissolve either way
10mg in 1ml is 10mg/ml, so 2.5mg is 25 units. thats the one i use, for what its worth
a slightly collapsed cake is cosmetic. a puddle in the bottom is not
label the date too. you will not remember which vial is which by week 18