maths check the cake shrinking is not a defect. it collapses as the water sublimes and it can look ugly, the volume is the variable, the dose is not
the cake collapsing on one side is how
Spun off from a message in #reconstitution on 2025-08-28. 9 messages, 4 participants.
- bpc_sceptic — the cake collapsing on one side is how it dried under vacuum, not a defect, measured, not guessed. thats 5mg/ml pick the volume so your dose is a whole number of units. thats the entire trick 12:51
single use, sterile is fine
i reconstitute in the evening and use it the next morning. it gives the cake time to go properly clear, measured, not guessed
a vial that has been shaken hard is not automatically ruined, but i would not swear it is intact
maths check bac water with benzyl alcohol if the vial is going to be opened more than about six times
i label every vial with date reconstituted and mg/ml in marker. future me has thanked present me twice
30mg in 3ml is 10mg/ml, so 5mg is 50 units. half the barrel, feels like a lot but its right, the volume is the variable, the dose is not
the vacuum in a lyophilised vial is real. hold the plunger or it will pull the whole thing in
a slightly collapsed cake is cosmetic. a puddle in the bottom is not