vialroom

#retatrutide 2024-04-07

Sunday26 messages6 participantstimes are UTC
Highlights from this day
  • slow.taper — the heart rate thing is real enough that i mention it whenever someone asks about starting 17:25
  • split_dose_sam — PeptideMeter came back 96.8 on one lot and 99 on the next from the same GGPeps, both fine 18:22
  • VialBot — Archive lookup: u100_pat first appears in this channel on 2024-01-01. 18:50
  • split_dose_sam — lost 37kg over 23 months at doses well under what the trials used 19:23
  • u100_pat — stopped for 9 months and restarted at half my old dose, the ramp was easier second time the glucagon arm is the mechanistic story for extra energy expenditure and its… 21:20
BR

coming back to this GI was about the same as tirzepatide for me, the difference was how fast it arrived

right so blood pressure stayed flat for me while heart rate moved, which i didnt expect

👍2🧊1

i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind

ST

sat at 12 for 5 months rather than climbing and it kept working, so i never went up

the half life supports weekly dosing and thats what ive done from the start

glucagon is the new bit

ST

the heart rate thing is real enough that i mention it whenever someone asks about starting

baseline  58
wk 2      61
wk 4      64
wk 6      67
wk 8      66
wk 10     65   (held dose from wk 7)
SD

i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps

watching my heart rate

SD

PeptideMeter came back 96.8 on one lot and 99 on the next from the same GGPeps, both fine

VI

unrelated but is there any long term safety data at all or is it phase 2 and hope

VB

Archive lookup: u100_pat first appears in this channel on 2024-01-01.

U1

im at 2.5 and the appetite effect is stronger than i expected, normal

how do people square the research use only framing with logging their own use

SD

lost 37kg over 23 months at doses well under what the trials used

🎉2❤️913
SD

research use only is on every vial and i treat it as exactly that, nobody here is prescribing

U1

phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan

U1

my resting rate went up 7 bpm in the first month and came back most of the way by month 1

stopped for 9 months and restarted at half my old dose, the ramp was easier second time
the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me