phase 2 was still trending at the end which is why the phase 3 readout matters more than usual
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#retatrutide 2024-08-29
Thursday33 messages7 participantstimes are UTC
Highlights from this day
- apob_over_ldl — phase 2 was still trending at the end which is why the phase 3 readout matters more than usual 14:28
- apob_over_ldl — low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom 14:35
- VialBot — Inter-lab diff for lot A-2418: 99.2% vs 96.8%. Within expected range. 14:36
- pinch_not_stretch — VendorInvestigate came back 97.4 on one lot and 96.8 on the next from the same WWB, both fine 16:15
- VialBot — Purity check: no report on file for lot A-2601. Nothing logged either way. 16:32
low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom
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Inter-lab diff for lot A-2418: 99.2% vs 96.8%. Within expected range.
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sat at 2.4 for 5 months rather than climbing and it kept working, so i never went up
genuine question the half life supports weekly dosing and thats what ive done from the start
i said 7 months ago that my heart rate had settled and it has stayed settled since
triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history
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quick one triple agonist meaning GLP-1, GIP and glucagon, have i got that right
anyone stayed at 15 for months rather than climbing
did anyone come off because of the heart rate
unrelated but whats a sensible starting point, im seeing everything from 0.5 to 2
watching my heart rate
did the phase 2 plateau or was it still moving at the end
for the archive back after 5 months, has anything actually been published since
stopped for 6 months and restarted at half my old dose, the ramp was easier second time
genuine question energy expenditure isnt something i could feel, though my sleep tracker disagreed with me, for what its worth
VendorInvestigate came back 97.4 on one lot and 96.8 on the next from the same WWB, both fine
why does everyone insist on smaller steps here than on the other two
research use only
Purity check: no report on file for lot A-2601. Nothing logged either way.
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whats the half life like, is it weekly the same way
anyone logging resting heart rate on this
i log resting heart rate every morning because of this and its the one number i actually watch
the heart rate thing is real enough that i mention it whenever someone asks about starting, for what its worth
quick one phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan
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people insist on small steps because the side effects arrive faster than on the other two
stopped for 17 months and restarted at half my old dose, the ramp was easier second time
17:36ferrous_ash pinned a message
blood pressure stayed flat for me while heart rate moved, which i didnt expect
mine went up too
right so appetite suppression at 15 was stronger than my tirzepatide experience at a comparable point, your mileage will differ
logging rhr daily
glucagon is the new bit
is the phase 2 dosing anywhere near what people here run
anyone reconstituting 40 vials to 5 so the steps come out smaller
no long term data