#retatrutide 2024-09-22

Sunday22 messages5 participantstimes are UTC

Highlights from this day

batch_bandit — there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists 20:00
group_buy_gwen — triple agonist meaning GLP-1, GIP and glucagon, have i got that right 20:14
swab_dry_first — the purity spread across lots worries me more than the molecule does, ill dig out the number 21:04

came off at 6 weeks because my resting rate stayed elevated and i didnt like it

mine went up too

low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom

glucagon is the new bit

there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists

baseline  58
wk 2      61
wk 4      64
wk 6      67
wk 8      66
wk 10     65   (held dose from wk 7)

triple agonist meaning GLP-1, GIP and glucagon, have i got that right

baseline  58
wk 2      61
wk 4      64
wk 6      67
wk 8      66
wk 10     65   (held dose from wk 7)

logging rhr daily

triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history

while im here how slow is low and slow here, four weeks a step or longer

TRIUMPH is phase 3

[edited]

anyone logging resting heart rate on this

triple agonist yeah

the purity spread across lots worries me more than the molecule does, ill dig out the number

baseline  58
wk 2      61
wk 4      64
wk 6      67
wk 8      66
wk 10     65   (held dose from wk 7)

held at 12 for 16 months and it never plateaued for me, which i cant explain

phase 2 only

watching my heart rate

is there any long term safety data at all or is it phase 2 and hope

coming back to this is the GI worse than tirzepatide or about the same

the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial

research use only

GI was about the same as tirzepatide for me, the difference was how fast it arrived

🔥3

how long before people saw the first change at 10