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#retatrutide 2024-10-16

Wednesday38 messages7 participantstimes are UTC
Highlights from this day
  • customs_owl — anyone stayed at 12 for months rather than climbing 15:26
  • spare_vial — why does everyone insist on smaller steps here than on the other two 15:55
  • tenpence — buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely 16:45
  • triple_ag_tom — the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me 16:50
  • customs_owl — the half life supports weekly dosing and thats what ive done from the start 18:35
CO

anyone stayed at 12 for months rather than climbing

fridge-temps.csv
648 rows · not retained in the public archive

research use only

TE

does the glucagon arm explain the heart rate or is that unrelated

TE

reconstituted the 15 vial to 8mg/ml specifically so i could take 0.25 without measuring crumbs

TRIUMPH is phase 3

SV

why does everyone insist on smaller steps here than on the other two

🎉3❤️2⚠️12
AA

the honest position is this has less human evidence behind it than anything else discussed here

anyone logging resting heart rate on this

is TRIUMPH the phase 3 programme

SV

phase 2 was still trending at the end which is why the phase 3 readout matters more than usual

settled by month three

🎉2

is the phase 2 dosing anywhere near what people here run

AA

low and slow

[edited]
baseline  58
wk 2      61
wk 4      64
wk 6      67
wk 8      66
wk 10     65   (held dose from wk 7)
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people insist on small steps because the side effects arrive faster than on the other two

TE

appetite suppression at 1.7 was stronger than my tirzepatide experience at a comparable point

buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely

📉11❤️15🎉15

my resting heart rate is up about 3 bpm, did that settle for anyone

watching my heart rate

TA

the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me

SV

unrelated but i said 8 months ago that my heart rate had settled and it has stayed settled since

anyone reconstituting 15 vials to 10 so the steps come out smaller

AP

the heart rate thing is real enough that i mention it whenever someone asks about starting

TE

GI was about the same as tirzepatide for me, the difference was how fast it arrived

CO

the half life supports weekly dosing and thats what ive done from the start

📈15❤️13
TE

came off at 20 weeks because my resting rate stayed elevated and i didnt like it

TE

i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps