coming back to this anyone gone above 0.25 and what changed
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#retatrutide 2024-12-13
Friday42 messages9 participantstimes are UTC
Highlights from this day
- low_and_slow — coming back to this anyone gone above 0.25 and what changed 21:37
- c18_column — quick one anyone stayed at 2.4 for months rather than climbing 22:04
- peak_split — does the glucagon arm explain the heart rate or is that unrelated the half life supports weekly dosing and thats what ive done from the start 22:32
sat at 1.7 for 6 months rather than climbing and it kept working, so i never went up
logging rhr daily
triple agonist yeah
im at 0.5 and the appetite effect is stronger than i expected, normal
TRIUMPH is phase 3
settled by month three
watching my heart rate
baseline 58
wk 2 61
wk 4 64
wk 6 67
wk 8 66
wk 10 65 (held dose from wk 7)🤝10😂1
no long term data
people insist on small steps because the side effects arrive faster than on the other two
*VendorInvestigate not the other one
slightly off topic but stopped for 13 months and restarted at half my old dose, the ramp was easier second time
*VendorInvestigate not the other one
quick one anyone stayed at 2.4 for months rather than climbing
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triple agonist meaning GLP-1, GIP and glucagon, have i got that right
held mine ages
cant feel it honestly
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stepping in 1 increments instead of doubling is the only thing i would change if i started again
right so lost 48kg over 12 months at doses well under what the trials used
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i log resting heart rate every morning because of this and its the one number i actually watch
the honest position is this has less human evidence behind it than anything else discussed here
follow up nobody should read my log as a plan, im recording what i did and thats all it is
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is the glucagon arm what people mean by the energy expenditure thing
genuine question held at 0.25 for 23 months and it never plateaued for me, which i cant explain
did anyone come off because of the heart rate
baseline 58
wk 2 61
wk 4 64
wk 6 67
wk 8 66
wk 10 65 (held dose from wk 7)does the glucagon arm explain the heart rate or is that unrelated
the half life supports weekly dosing and thats what ive done from the start
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back after 16 months, has anything actually been published since
research use only
[edited]mine went up too
the purity spread across lots worries me more than the molecule does
reconstituted the 15 vial to 4mg/ml specifically so i could take 10 without measuring crumbs
coming back to this TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule
the heart rate thing is real enough that i mention it whenever someone asks about starting
why does everyone insist on smaller steps here than on the other two
quick one my resting rate went up 2 bpm in the first month and came back most of the way by month 4
the honest position is this has less human evidence behind it than anything else discussed here
[edited]glucagon is the new bit
smaller steps here
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no idea whether the heart rate settles for everyone, mine did and one log isnt data
low and slow
i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind
how slow is low and slow here, four weeks a step or longer
the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial
appetite suppression at 1.7 was stronger than my tirzepatide experience at a comparable point
blood pressure stayed flat for me while heart rate moved, which i didnt expect