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#retatrutide 2025-01-13

Monday20 messages4 participantstimes are UTC
Highlights from this day
  • ruo_only — the purity spread across lots worries me more than the molecule does 18:59
  • freeze_thaw — there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists 20:49
  • freeze_thaw — held at 1.7 for 18 months and it never plateaued for me, which i cant explain, happy to be corrected 20:50
RO

the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me

the purity spread across lots worries me more than the molecule does

🎉15👍17❤️1

appetite suppression at 15 was stronger than my tirzepatide experience at a comparable point, ill dig out the number

*Medutest not the other one

AA

whats a sensible starting point, im seeing everything from 0.5 to 2

WZ

does the energy expenditure claim show up as anything you can feel

coming back to this how long before people saw the first change at 1.7

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RO

phase 2 was still trending at the end which is why the phase 3 readout matters more than usual

mine went up too

[edited]
baseline  58
wk 2      61
wk 4      64
wk 6      67
wk 8      66
wk 10     65   (held dose from wk 7)

triple agonist yeah

Medutest came back 99.4 on one lot and 98.6 on the next from the same BCH, both fine

FT

there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists

🙏14👍15

held at 1.7 for 18 months and it never plateaued for me, which i cant explain, happy to be corrected

🤝14👍15🧊18

low and slow

whats the half life like, is it weekly the same way