vialroom

#retatrutide 2025-01-15

Wednesday21 messages5 participantstimes are UTC
Highlights from this day
  • nhs_pathway_nell — VendorInvestigate came back 99.2 on one lot and 98.1 on the next from the same JEEP, both fine 20:45
  • pinch_not_stretch — is there any long term safety data at all or is it phase 2 and hope 20:51
  • nhs_pathway_nell — reconstituted the 2 vial to 10mg/ml specifically so i could take 7.5 without measuring crumbs 21:00
  • nhs_pathway_nell — my resting heart rate is up about 5 bpm, did that settle for anyone 21:49
  • pinch_not_stretch — anyone stayed at 5 for months rather than climbing 22:50
NP

stepping in 2.5 increments instead of doubling is the only thing i would change if i started again

NP

there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists

LL

is the glucagon arm what people mean by the energy expenditure thing

settled by month three

NP

VendorInvestigate came back 99.2 on one lot and 98.1 on the next from the same JEEP, both fine

❤️1🤝2😂1
PN

is there any long term safety data at all or is it phase 2 and hope

Cited study
Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial
New England Journal of Medicine · 2023
48 weeks, dose-ranging. A Phase 2 result is not a safety record.

nobody should read my log as a plan, im recording what i did and thats all it is

🤝8

came off at 2 weeks because my resting rate stayed elevated and i didnt like it

NP

right so the honest position is this has less human evidence behind it than anything else discussed here

VB

Channel stats, last 30 days: 97 messages from 37 members.

PN

the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me

PN

anyone stayed at 5 for months rather than climbing

Cited study
Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial
New England Journal of Medicine · 2023
48 weeks, dose-ranging. A Phase 2 result is not a safety record.

why does everyone insist on smaller steps here than on the other two

PN

the heart rate thing is real enough that i mention it whenever someone asks about starting
phase 2 was still trending at the end which is why the phase 3 readout matters more than usual