vialroom

#retatrutide 2025-01-19

Sunday14 messages4 participantstimes are UTC
Highlights from this day
  • pbs_pip — research use only is on every vial and i treat it as exactly that, nobody here is prescribing 03:19
  • pbs_pip — the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me 04:27
  • dublin_dose — unrelated but appetite suppression at 2 was stronger than my tirzepatide experience at a comparable point 05:08
PP

research use only is on every vial and i treat it as exactly that, nobody here is prescribing

PP

phase 2 only

Cited study
Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial
New England Journal of Medicine · 2023
48 weeks, dose-ranging. A Phase 2 result is not a safety record.
🔥4
SS

coming back to this anyone logging resting heart rate on this

stopped for 20 months and restarted at half my old dose, the ramp was easier second time

VI

triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history

PP

glucagon is the new bit

Cited study
Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial
New England Journal of Medicine · 2023
48 weeks, dose-ranging. A Phase 2 result is not a safety record.

the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me

🤝1❤️1🔥15

sat at 2 for 4 months rather than climbing and it kept working, so i never went up

[edited]

blood pressure stayed flat for me while heart rate moved, which i didnt expect

SS

triple agonist meaning GLP-1, GIP and glucagon, have i got that right

DD

unrelated but appetite suppression at 2 was stronger than my tirzepatide experience at a comparable point