right so the honest position is this has less human evidence behind it than anything else discussed here
#retatrutide 2025-01-30
Thursday33 messages8 participantstimes are UTC
Highlights from this day
- no_chargeback — stopped for 22 months and restarted at half my old dose, the ramp was easier second time i was wrong to call the heart rate a non issue last year, enough people… 20:38
- ms_ms_mira — anyone compared their VendorInvestigate purity across two different KP lots triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long… 21:35
- ms_ms_mira — people insist on small steps because the side effects arrive faster than on the other two, ill dig out the number 21:38
- forty_units — anyone reconstituting 20 vials to 2.5 so the steps come out smaller 22:30
- logrotate — nobody should read my log as a plan, im recording what i did and thats all it is 23:00
while im here buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely
does the energy expenditure claim show up as anything you can feel
[edited]watching my heart rate
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i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind
anyone tracking blood pressure alongside the heart rate
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no long term data
is there any long term safety data at all or is it phase 2 and hope
triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history
stopped for 22 months and restarted at half my old dose, the ramp was easier second time
i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind
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back after 10 months, has anything actually been published since
the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me, ill dig out the number
is TRIUMPH the phase 3 programme
came off at 15 weeks because my resting rate stayed elevated and i didnt like it
the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial, for what its worth
mine went up too
anyone logging resting heart rate on this
follow up i log resting heart rate every morning because of this and its the one number i actually watch
anyone compared their VendorInvestigate purity across two different KP lots
triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history
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people insist on small steps because the side effects arrive faster than on the other two, ill dig out the number
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low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom
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how slow is low and slow here, four weeks a step or longer
my resting heart rate is up about 2 bpm, did that settle for anyone
why does everyone insist on smaller steps here than on the other two
while im here my resting rate went up 4 bpm in the first month and came back most of the way by month 18
is the glucagon arm what people mean by the energy expenditure thing
the half life supports weekly dosing and thats what ive done from the start
anyone reconstituting 20 vials to 2.5 so the steps come out smaller
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low and slow
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i said 7 months ago that my heart rate had settled and it has stayed settled since, for what its worth
nobody should read my log as a plan, im recording what i did and thats all it is
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reconstituted the 40 vial to 4mg/ml specifically so i could take 1 without measuring crumbs
slightly off topic but did anyone come off because of the heart rate
phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan